A Chlorfenapyr Mixture Net Interceptor® G2 Shows High Efficacy and Wash Durability against Resistant Mosquitoes in West Africa
N’Guessan R, Odjo A, Ngufor C, … Rowland M
2016PLoS ONEcited 121 timesFirst authorOpen access
All projects
Nets that kill resistant mosquitoes
2015 to todayOngoing
Benin, Côte d'Ivoire and Tanzania
Chlorfenapyr kills mosquitoes by disrupting their energy production, so pyrethroid resistance does not protect them. From adapted laboratory tests to hut trials and a three-arm cluster randomised trial in Côte d'Ivoire, these studies follow the new generation of nets.
Results
- In Benin, Interceptor G2 killed 71% of resistant mosquitoes against 20% for a standard net, and still 65% after 20 washesPLoS ONE, 2016
- At M'bé in Côte d'Ivoire, PRONet Duo killed 84% of mosquitoes against 72% for Interceptor G2Frontiers in Malaria, 2025
Articles
The activity of the pyrrole insecticide chlorfenapyr in mosquito bioassay: towards a more rational testing and screening of non-neurotoxic insecticides for malaria vector control
Oxborough RM, N’Guessan R, Jones R, … Rowland M
2015Malaria Journalcited 132 timesOpen access
PRONet Duo insecticide-treated net incorporated with chlorfenapyr and bifenthrin is superior to Interceptor® G2 nets against pyrethroid-resistant Anopheles gambiae sensu lato: a randomized experimental hut trial in Côte d’Ivoire and Tanzania using non-inferiority design
Assenga AA, Alou LPA, Camara S, … Moore S
2025Frontiers in Malariacited 5 timesOpen access
Efficacy of chlorfenapyr-pyrethroid and piperonyl butoxide-pyrethroid long-lasting insecticidal nets (LLINs) compared to pyrethroid-only LLINs for malaria control in Côte d’Ivoire: a three group, cluster randomised trial
Sih C, Protopopoff N, KOFFI AA, … Cook JA
2024Trialscited 11 timesOpen access